Successful treatment of steroid resistant hypereosinophilic syndrome with low-dose CsA
نویسندگان
چکیده
REFERENCES 1. Mayer B, Yurek S, Kiesewetter H, Salama A. Mixed-type autoimmune hemolytic anemia: differential diagnosis and a critical review of reported cases. Transfusion 2008;48:2229-34. 2. Sudha Reddy VR, Samayam P, Ravichander B, Bai U. Autoimmune hemolytic anemia: mixed type-a case report. Indian J Hematol Blood Transfus 2011;27:107-10. 3. Hoffman PC. Immune hemolytic anemia-selected topics. Hematology Am Soc Hematol Educ Program 2009:80-6. 4. Tsiopoulos FD, Manolakis AC, Kapsoritakis AN, Psychos AK, Potamianos SP. Autoimmune hemolytic anemia and ophthalmic artery thrombosis preceding the intestinal manifestations of Crohn's disease. Inflamm Bowel Dis 2009;15:487-8. 5. Kowal-Vern A, Radhakrishnan J, Goldman J, Hutchins W, Blank J. Mesenteric and portal vein thrombosis after splenectomy for autoimmune hemolytic anemia. J Clin Gastroenterol 1988;10: 108-10.
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We report a child with hypereosinophilic syndrome who presented with cardiogenic shock. In addition, she had skin and joint involvement. The clinical condition improved and eosinophil counts normalized with steroid therapy. However, the skin lesions and hypereosinophilia relapsed on stopping the steroids. The child was subsequently maintained in remission on low dose prednisolone.
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BACKGROUND In children, idiopathic nephrotic syndrome (INS) is primarily treated using corticosteroids. When remission is not achieved, the coadministration of potent immunosuppressant therapy becomes imperative. Cyclosporine A (CsA) is reportedly associated with a higher incidence of remission in comparison with other immunosuppressive agents. METHODS The present study investigated the respo...
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